Histone recognition and large-scale structural analysis of the human bromodomain family.
Bromodomains (BRDs) are protein interaction modules that specifically recognize ε-N-lysine acetylation motifs, a key event in the reading process of epigenetic marks. The 61 BRDs in the human genome cluster into eight families based on structure/sequence similarity. Here, we present 29 high-resoluti...
| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
2012
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