Characterisation of beta globin gene cluster deletions using multiplex-Gap-PCR and Multiplex Ligation-dependent Probe Amplification (MLPA)
Deletions in the beta (β)-globin gene cluster are usually rare, yet this type of mutation is problematic to detect, and subsequently possess a challenge in the diagnostic laboratory. Deletions in this cluster are usually related to the heterozygous of the delta beta thalassaemia (δβ-thalassaemia)...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | http://eprints.usm.my/56770/1/Dr.%20Yasmin%20Mohamad%20Redzuwan-24%20pages.pdf |