TOR Signaling Couples Oxygen Sensing to Lifespan in C. elegans ανά Michael Schieber, Navdeep S. Chandel

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Targeting fatty acid metabolism in glioblastoma ανά Jason Miska, Navdeep S. Chandel

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Genes Involved in Maintaining Mitochondrial Membrane Potential Upon Electron Transport Chain Disruption ανά Karthik Vasan, Matt Clutter, Sara Fernandez Dunne, Mariam D. George, Chi-Hao Luan, Navdeep S. Chandel, Navdeep S. Chandel, Inmaculada Martínez-Reyes

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Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members. ανά Colleen M Snyder, Emelyn H Shroff, Jing Liu, Navdeep S Chandel

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MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters ανά Dongmei Wang, Haimin Li, Navdeep S. Chandel, Yali Dou, Rui Yi

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The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia ανά Robert B. Hamanaka, Samuel E. Weinberg, Colleen R. Reczek, Navdeep S. Chandel

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A Drosophila model of mitochondrial disease phenotypic heterogeneity ανά Lucy Granat, Debbra Y. Knorr, Daniel C. Ranson, Ram Prosad Chakrabarty, Navdeep S. Chandel, Joseph M. Bateman

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The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses ανά Nathan Meade, Helen K. Toreev, Ram P. Chakrabarty, Charles R. Hesser, Chorong Park, Navdeep S. Chandel, Derek Walsh

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ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia ανά Tuan Anh Phu, Ngan K. Vu, Martin Ng, Alex S. Gao, Joshua S. Stoolman, Navdeep S. Chandel, Robert L. Raffai

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Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming ανά Ratnakar Tiwari, Prashant V. Bommi, Peng Gao, Matthew J. Schipma, Yalu Zhou, Susan E. Quaggin, Navdeep S. Chandel, Pinelopi P. Kapitsinou

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Hif1α-dependent mitochondrial acute O2 sensing and signaling to myocyte Ca2+ channels mediate arterial hypoxic vasodilation ανά Alejandro Moreno-Domínguez, Olalla Colinas, Ignacio Arias-Mayenco, José M. Cabeza, Juan L. López-Ogayar, Navdeep S. Chandel, Norbert Weissmann, Natascha Sommer, Alberto Pascual, José López-Barneo

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Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function ανά Zheng Fu, Jian Ye, Joseph W. Dean, John W. Bostick, Samuel E. Weinberg, Lifeng Xiong, Kristen N. Oliff, Zongming E. Chen, Dorina Avram, Navdeep S. Chandel, Liang Zhou

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Neurons undergo pathogenic metabolic reprogramming in models of familial ALS ανά Sean-Patrick Riechers, Jelena Mojsilovic-Petrovic, Tayler B. Belton, Ram P. Chakrabarty, Mehraveh Garjani, Valentina Medvedeva, Casey Dalton, Yvette C. Wong, Navdeep S. Chandel, Gerald Dienel, Robert G. Kalb

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Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis ανά William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, GR Scott Budigner, Navdeep S Chandel

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Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency. ανά Lucy Granat, Debbra Y Knorr, Daniel C Ranson, Emma L Hamer, Ram Prosad Chakrabarty, Francesca Mattedi, Laura Fort-Aznar, Frank Hirth, Sean T Sweeney, Alessio Vagnoni, Navdeep S Chandel, Joseph M Bateman

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Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations ανά Zibo Zhao, Kaixiang Cao, Jun Watanabe, Cassandra N. Philips, Jacob M. Zeidner, Yukitomo Ishi, Qixuan Wang, Sarah R. Gold, Katherine Junkins, Elizabeth T. Bartom, Feng Yue, Navdeep S. Chandel, Rintaro Hashizume, Issam Ben-Sahra, Ali Shilatifard

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α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease ανά Fanni F. Geibl, Martin T. Henrich, Zhong Xie, Enrico Zampese, Jun Ueda, Tatiana Tkatch, David L. Wokosin, Elena Nasiri, Constantin A. Grotmann, Valina L. Dawson, Ted M. Dawson, Navdeep S. Chandel, Wolfgang H. Oertel, D. James Surmeier

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Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells ανά Adam Naguib, Grinu Mathew, Colleen R. Reczek, Kaitlin Watrud, Alexandra Ambrico, Tali Herzka, Irene Casanova Salas, Matthew F. Lee, Nour El-Amine, Wu Zheng, M. Emilia Di Francesco, Joseph R. Marszalek, Darryl J. Pappin, Navdeep S. Chandel, Lloyd C. Trotman

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Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice ανά Gregory S. McElroy, Ram P. Chakrabarty, Karis B. D’Alessandro, Karthik Vasan, Jerica Tan, Joshua S. Stoolman, Samuel E. Weinberg, Elizabeth M. Steinert, Paul A. Reyfman, Benjamin D. Singer, Warren C. Ladiges, Lin Gao, José Lopéz-Barneo, G. R. Scott Budinger, Navdeep S. Chandel

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Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis ανά Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver

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