Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis
Summary Heart development requires organized integration of actin filaments into the sarcomere, the contractile unit of myofibrils, although it remains largely unknown how actin filaments are assembled during myofibrillogenesis. Here we show that Fhod3, a member of the formin family of proteins that...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-07-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/1/9/889 |