Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis

Summary Heart development requires organized integration of actin filaments into the sarcomere, the contractile unit of myofibrils, although it remains largely unknown how actin filaments are assembled during myofibrillogenesis. Here we show that Fhod3, a member of the formin family of proteins that...

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Bibliographic Details
Main Authors: Meikun Kan-O, Ryu Takeya, Takaya Abe, Naoyuki Kitajima, Motohiro Nishida, Ryuji Tominaga, Hitoshi Kurose, Hideki Sumimoto
Format: Article
Language:English
Published: The Company of Biologists 2012-07-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/1/9/889