Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection

Mikaeloff et al. use untargeted and targeted LC-MS/MS-based plasma metabolic profiling to discover dysregulated metabolism including that of glutaminolysis in individuals living with HIV. Furthermore, decreased levels of neurosteroids were detected suggesting a potential connection between HIV and n...

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Main Authors: Flora Mikaeloff, Sara Svensson Akusjärvi, George Mondinde Ikomey, Shuba Krishnan, Maike Sperk, Soham Gupta, Gustavo Daniel Vega Magdaleno, Alejandra Escós, Emilia Lyonga, Marie Claire Okomo, Claude Tayou Tagne, Hemalatha Babu, Christian L. Lorson, Ákos Végvári, Akhil C. Banerjea, Julianna Kele, Luke Elizabeth Hanna, Kamal Singh, João Pedro de Magalhães, Rui Benfeitas, Ujjwal Neogi
格式: Article
語言:English
出版: Nature Portfolio 2022-01-01
叢編:Communications Biology
在線閱讀:https://doi.org/10.1038/s42003-021-02985-3