Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin
Peptide modification is used to optimize the transport of saporin specifically to cancer cells in vitro and in vivo, where it exerts anti-cancer actions.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04385-7 |
| _version_ | 1797945761535623168 |
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| author | Curtis A. Allred Claire Gormley Indu Venugopal Shunzi Li Michael J. McGuire Kathlynn C. Brown |
| author_facet | Curtis A. Allred Claire Gormley Indu Venugopal Shunzi Li Michael J. McGuire Kathlynn C. Brown |
| author_sort | Curtis A. Allred |
| collection | DOAJ |
| description | Peptide modification is used to optimize the transport of saporin specifically to cancer cells in vitro and in vivo, where it exerts anti-cancer actions. |
| first_indexed | 2024-04-10T21:00:15Z |
| format | Article |
| id | doaj.art-af0f56e6289749cea0b0fa9a291b745b |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-10T21:00:15Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-af0f56e6289749cea0b0fa9a291b745b2023-01-22T12:22:05ZengNature PortfolioCommunications Biology2399-36422023-01-016111110.1038/s42003-022-04385-7Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxinCurtis A. Allred0Claire Gormley1Indu Venugopal2Shunzi Li3Michael J. McGuire4Kathlynn C. Brown5SRI International, Biosciences DivisionSRI International, Biosciences DivisionSRI International, Biosciences DivisionSRI International, Biosciences DivisionSRI International, Biosciences DivisionSRI International, Biosciences DivisionPeptide modification is used to optimize the transport of saporin specifically to cancer cells in vitro and in vivo, where it exerts anti-cancer actions.https://doi.org/10.1038/s42003-022-04385-7 |
| spellingShingle | Curtis A. Allred Claire Gormley Indu Venugopal Shunzi Li Michael J. McGuire Kathlynn C. Brown Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin Communications Biology |
| title | Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin |
| title_full | Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin |
| title_fullStr | Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin |
| title_full_unstemmed | Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin |
| title_short | Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin |
| title_sort | tumor specific intracellular delivery peptide guided transport of a catalytic toxin |
| url | https://doi.org/10.1038/s42003-022-04385-7 |
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