Subtype-specific expression of MELK is partly due to copy number alterations in breast cancer.

Subtype-specific expression of MELK is partly due to copy number alterations in breast cancer.

Maternal embryonic leucine-zipper kinase (MELK) regulates cell cycle progression and is highly expressed in many cancers. The molecular mechanism of MELK dysregulation has not been determined in aggressive forms of breast cancer, such as triple negative breast cancer (TNBC). To evaluate molecular ma...

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Bibliographic Details
Main Authors: Ashley A Hardeman, Yoo Jane Han, Tatyana A Grushko, Jeffrey Mueller, Maria J Gomez, Yonglan Zheng, Olufunmilayo I Olopade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0268693

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https://doi.org/10.1371/journal.pone.0268693

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