The impact of serotype-specific vaccination on phylodynamic parameters of Streptococcus pneumoniae and the pneumococcal pan-genome.
In the United States, the introduction of the heptavalent pneumococcal conjugate vaccine (PCV) largely eliminated vaccine serotypes (VT); non-vaccine serotypes (NVT) subsequently increased in carriage and disease. Vaccination also disrupts the composition of the pneumococcal pangenome, which include...
Main Authors: | , , , , , , , , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Public Library of Science (PLoS)
2018-04-01
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סדרה: | PLoS Pathogens |
גישה מקוונת: | http://europepmc.org/articles/PMC5902063?pdf=render |