Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation

Post-transcriptional modifications of transfer RNAs (tRNAs) have long been recognized to play crucial roles in regulating the rate and fidelity of translation. However, the extent to which they determine global protein production remains poorly understood. Here we use quantitative proteomics to show...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Deng, Wenjun, Babu, I. Ramesh, Su, Dan, Yin, Shanye, Begley, Thomas J., Dedon, Peter C.
مؤلفون آخرون: Massachusetts Institute of Technology. Department of Biological Engineering
التنسيق: مقال
اللغة:en_US
منشور في: Public Library of Science 2016
الوصول للمادة أونلاين:http://hdl.handle.net/1721.1/100584
https://orcid.org/0000-0003-0011-3067