Cp2ZrMeCl: A reagent for asymmetric methyl addition.

The use of Cp2ZrMeCl is described as a source of nucleophilic methyl in asymmetric catalysis. This easily prepared reagent is bench stable, weighable in air, and generally useful in highly enantioselective copper-catalyzed addition reactions at room temperature. Methyl is successfully (generally &am...

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Detalhes bibliográficos
Principais autores: Fletcher, S, Garrec, K
Formato: Journal article
Publicado em: American Chemical Society 2016