A cascade strategy enables a total synthesis of (-)-gephyrotoxin.

A cascade strategy enables a total synthesis of (-)-gephyrotoxin.

A concise and efficient synthesis of (-)-gephyrotoxin from L-pyroglutaminol has been realized. The key step in this approach is a diastereoselective intramolecular enamine/Michael cascade reaction that forms two rings and two stereocenters and generates a stable tricyclic iminium cation. A hydroxy-d...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Chu, S, Wallace, S, Smith, M
Format:	Journal article
Język:	English
Wydane:	Wiley 2014

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