An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.

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Cushing's syndrome, which is characterized by excessive circulating glucocorticoid concentrations, may be due to ACTH-dependent or -independent causes that include anterior pituitary and adrenal cortical tumors, respectively. ACTH secretion is stimulated by CRH, and we report a mouse model for...

Bibliografske podrobnosti
Main Authors:	Bentley, L, Esapa, C, Nesbit, M, Head, R, Evans, H, Lath, D, Scudamore, C, Hough, T, Podrini, C, Hannan, F, Fraser, W, Croucher, P, Brown, M, Brown, S, Cox, R, Thakker, R
Format:	Journal article
Jezik:	English
Izdano:	2014

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