The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.

The positive transcription elongation factor b (P-TEFb) (CDK9/cyclin T (CycT)) promotes mRNA transcriptional elongation through phosphorylation of elongation repressors and RNA polymerase II. To understand the regulation of a transcriptional CDK by its cognate cyclin, we have determined the structur...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Baumli, S, Lolli, G, Lowe, E, Troiani, S, Rusconi, L, Bullock, A, Debreczeni, J, Knapp, S, Johnson, L
Format: Journal article
Język:English
Wydane: 2008