Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity.

The major heat-inducible Hsp70 is a potent survival protein that confers cytoprotection against numerous death-inducing stimuli and increases the tumorigenicity of rodent cells. The depletion of Hsp70 by adenovirus-mediated transfer of antisense cDNA induces caspase-independent death of tumorigenic...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Gyrd-Hansen, M, Nylandsted, J, Jäättelä, M
التنسيق: Journal article
اللغة:English
منشور في: 2004