Renal targeting potential of a polymeric drug carrier, poly-L-glutamic acid, in normal and diabetic rats
Background and purpose: Poly-l-glutamic acid (PG) has been used widely as a carrier to deliver anticancer chemotherapeutics. This study evaluates PG as a selective renal drug carrier. Experimental approach: 3H-deoxycytidine-labeled PGs (17 or 41 kDa) and 3H-deoxycytidine were administered intravenou...
Main Authors: | Chai, H.J., Kiew, L.V., Chin, Y., Norazit, A., Noor, S.M., Lo, Y.L., Looi, C.Y., Lau, Y.S., Lim, T.M., Wong, W.F., Abdullah, N.A., Sattar, M.Z.A., Johns, E.J., Chik, Z., Chung, L.Y. |
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Format: | Article |
Published: |
Dove Medical Press
2017
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