Eukaryotic-driven directed evolution of Cas9 nucleases

Abstract Background Further advancement of genome editing highly depends on the development of tools with higher compatibility with eukaryotes. A multitude of described Cas9s have great potential but require optimization for genome editing purposes. Among these, the Cas9 from Campylobacter jejuni, C...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Giulia Vittoria Ruta, Matteo Ciciani, Eyemen Kheir, Michele Domenico Gentile, Simone Amistadi, Antonio Casini, Anna Cereseto
स्वरूप: लेख
भाषा:English
प्रकाशित: BMC 2024-03-01
श्रृंखला:Genome Biology
ऑनलाइन पहुंच:https://doi.org/10.1186/s13059-024-03215-9