huva: A human variation analysis framework to predict gene perturbation from population-scale multi-omics data

huva: A human variation analysis framework to predict gene perturbation from population-scale multi-omics data

Summary: Variance of gene expression is intrinsic to any given natural population. Here, we present a protocol to analyze this variance using a conditional quasi loss- and gain-of-function approach. The huva (human variation) package takes advantage of population-scale multi-omics data to infer gene...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Anna C. Aschenbrenner, Lorenzo Bonaguro
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2023-06-01
Cyfres:STAR Protocols
Pynciau:
Bioinformatics
RNAseq
Immunology
Gene Expression
Systems Biology
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S266616672300151X

Rhyngrwyd

http://www.sciencedirect.com/science/article/pii/S266616672300151X

Eitemau Tebyg