KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43
Abstract Background Ossification of ligamentum flavum (OLF) is a prevalent degenerative spinal disease, typically causing severe neurological dysfunction. Kruppel-like factor 5 (KLF5) plays an essential role in the regulation of skeletal development. However, the mechanism KLF5 plays in OLF remains...
Những tác giả chính: | , , , , , |
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Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
BMC
2024-04-01
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Loạt: | Journal of Orthopaedic Surgery and Research |
Những chủ đề: | |
Truy cập trực tuyến: | https://doi.org/10.1186/s13018-024-04702-2 |