Filtering next-generation sequencing of the Ig gene repertoire data using antibody structural information

Next-generation sequencing of the immunoglobulin gene repertoire (Ig-seq) produces large volumes of information at the nucleotide sequence level. Such data have improved our understanding of immune systems across numerous species and have already been successfully applied in vaccine development and...

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Detalhes bibliográficos
Main Authors: Kovaltsuk, A, Krawczyk, K, Kelm, S, Snowden, J, Deane, C
Formato: Journal article
Publicado em: American Association of Immunologists 2018