Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS).

Deacetoxycephalosporin C synthase (DAOCS) is an iron(II) and 2-oxoglutarate-dependent oxygenase that catalyzes the conversion of penicillin N to deacetoxycephalosporin C, the committed step in the biosynthesis of cephalosporin antibiotics. The crystal structure of DAOCS revealed that the C terminus...

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Détails bibliographiques
Auteurs principaux: Lee, H, Lloyd, MD, Harlos, K, Clifton, I, Baldwin, J, Schofield, C
Format: Journal article
Langue:English
Publié: 2001