Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.

Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.

BACKGROUND:Pneumolysin (PLN) is an intracellular toxin of Streptococcus pneumoniae that has been implicated as a major virulence factor in infections caused by this pathogen. Conserved bacterial motifs are recognized by the immune system by pattern recognition receptors among which the family of Tol...

书目详细资料
Main Authors:	Mark C Dessing, Robert A Hirst, Alex F de Vos, Tom van der Poll
格式:	文件
语言:	English
出版:	Public Library of Science (PLoS) 2009-11-01
丛编:	PLoS ONE
在线阅读:	http://europepmc.org/articles/PMC2776357?pdf=render

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