Common variants at 11p13 are associated with susceptibility to tuberculosis.

Common variants at 11p13 are associated with susceptibility to tuberculosis.

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After imputation of data from the 1000 Genomes Project into a genome-wide dataset of Ghanaian individuals with tuberculosis and controls, we identified a resistance locus on chromosome 11p13 downstream of the WT1 gene (encoding Wilms tumor 1). The strongest signal was obtained at the rs2057178 SNP (...

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Bibliographic Details
Main Authors: Thye, T, Owusu-Dabo, E, Vannberg, F, van Crevel, R, Curtis, J, Sahiratmadja, E, Balabanova, Y, Ehmen, C, Muntau, B, Ruge, G, Sievertsen, J, Gyapong, J, Nikolayevskyy, V, Hill, P, Sirugo, G, Drobniewski, F, van de Vosse, E, Newport, M, Alisjahbana, B, Nejentsev, S, Ottenhoff, T, Hill, A, Horstmann, R, Meyer, C
Format: Journal article
Language:English
Published: 2012

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