Thickness of the aqueous boundary layer in stirred microtitre plate permeability assays (PAMPA and Caco-2), based on the Levich equation

Thickness of the aqueous boundary layer in stirred microtitre plate permeability assays (PAMPA and Caco-2), based on the Levich equation

The stirring frequency exponent of -1/2 in the theoretical Levich expression appears to apply to PAMPA and Caco-2 assays, where efficient individual-well magnetic stirring ( > 20 RPM) is used. If a single molecule is used as a stirring calibrant, then scaling suggested by Eq. (5) with microtitr...

Bibliografiset tiedot
Päätekijä:	Alex Avdeef
Aineistotyyppi:	Artikkeli
Kieli:	English
Julkaistu:	International Association of Physical Chemists (IAPC) 2022-12-01
Sarja:	ADMET and DMPK
Linkit:	http://pub.iapchem.org/ojs/index.php/admet/article/view/1568

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