Statistical power calculations for mixed pharmacokinetic study designs using a population approach

Simultaneous modelling of dense and sparse pharmacokinetic data is possible with a population approach. To determine the number of individuals required to detect the effect of a covariate, simulation-based power calculation methodologies can be employed. The Monte Carlo Mapped Power method (a simula...

Повний опис

Бібліографічні деталі
Автори: Kloprogge, F, Simpson, J, Day, N, White, N, Tarning, J
Формат: Journal article
Мова:English
Опубліковано: Springer New York LLC 2014

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