Comparison of T cell activities mediated by human TCRs and CARs that use the same recognition domains

Comparison of T cell activities mediated by human TCRs and CARs that use the same recognition domains

Adoptive T cell therapies have achieved significant clinical responses, especially in hematopoietic cancers. Two types of receptor systems have been used to redirect the activity of T cells, normal heterodimeric T-cell receptors (TCRs) or synthetic chimeric antigen receptors (CARs). TCRs recognize p...

書目詳細資料
Main Authors:	Harris, DT, Hager, MV, Smith, SN, Cai, Q, Stone, JD, Kruger, P, Lever, M, Dushek, O, Schmitt, TM, Greenberg, PD, Kranz, DM
格式:	Journal article
出版:	American Association of Immunologists 2017

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