Emerging epigenetic therapies: protein arginine methyltransferase inhibitors
Protein arginine methyltransferases (PRMTs) are key epigenetic mediators within cells, comprising a family of nine proteins each with its own unique role. They are able to regulate gene expression at several levels through the addition of methyl groups to arginine residues in both histone and nonhis...
Principais autores: | Pook, H, Pauklin, S |
---|---|
Outros Autores: | Gray, SG |
Formato: | Book section |
Idioma: | English |
Publicado em: |
Academic Press
2023
|
Registros relacionados
-
Small molecule inhibitors and substrate analyses of protein arginine methyltransferases
por: Varney, A
Publicado em: (2015) -
A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes
por: Iredia D. Iyamu, et al.
Publicado em: (2021-06-01) -
Protein Arginine Methyltransferases: Emerging Targets in Cardiovascular and Metabolic Disease
por: Yan Zhang, et al.
Publicado em: (2024-07-01) -
Synthesis and Activity of Triazole-Adenosine Analogs as Protein Arginine Methyltransferase 5 Inhibitors
por: Tyler Brown, et al.
Publicado em: (2022-06-01) -
Design, Synthesis and Biological Evaluation of Novel and Potent Protein Arginine Methyltransferases 5 Inhibitors for Cancer Therapy
por: Yixuan Tang, et al.
Publicado em: (2022-10-01)